Human biology can be complex, in part due to the function and interplay of the body’s approximately 37 trillion cells, which are organized into tissues, organs, and systems. However, recent advances ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Allosteric compounds offer an alternative mode of inhibition to orthosteric compounds ...

Logic gates are the foundational building blocks of digital computing, and their principles have been seamlessly integrated into the realm of programming. This article explores the importance, ...

Rheumatoid arthritis (RA) is a complex autoimmune disease with an unknown aetiology. However, rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) play a significant role in initiating and ...

In this tutorial, we will build our own programming language and compiler using Java (you can use any other language, preferably object-oriented). The purpose of the article is to help people who are ...

LiteX is a Python "front-end" that generates Verilog netlists, and drives proprietary build "back-ends", such as Vivado or ISE, to create bitstreams ("gateware") for FPGAs. LiteX is relies on a Python ...

A computational platform, Boolean network explorer (BoNE), has recently been developed to infuse AI-enhanced precision into drug discovery; it enables invariant Boolean Implication Networks of disease ...

In this manuscript, we address an essential question in developmental and evolutionary biology: How have changes in gene regulatory networks contributed to the invertebrate-to-vertebrate transition?

De novo design seeks to generate molecules with required property profiles by virtual design-make-test cycles. With the emergence of deep learning and neural generative models in many application ...

Cell classifier circuits are synthetic biological circuits capable of distinguishing between different cell states depending on specific cellular markers and engendering a state-specific response. An ...